Biomechanics Working Group

Working Group Leads

Beth Winkelstein (winkelst@seas.upenn.edu)

Yasin Dhaher (y-dhaher@northwestern.edu)

Muhammad Zaman (zaman@bu.edu)

Announcements


Goals and Objectives

Through interactions within members and with other working groups, the goals of the Biomechanics Working Group are

  • to establish a cross-discipline discussion platform for multiscale modeling and analysis issues in the general area of biomechanics

  • to identify computational infrastructure needs for multiscale biomechanical simulations

  • to establish pathways for experimental data and validation to support multiscale modeling and simulation in biomechanics

  • to increase awareness to the role of multiscale analysis in biomechanics and simulation-based medicine

  • to promote the role of dissemination to accelerate multiscale analysis in biomechanics

History

The Biomechanics Working Group has started in November 2010 following working group related discussions at the 2010 MSM CONSORTIUM MEETING. Founding co-leads of the working group were Jay Humphrey of Yale University and Ahmet Erdemir of Cleveland Clinic. The working group inherited the Working Group 6 - Tissue Mechanics, which was started by Trent Guess of University of Missouri, Kansas City.

Participants

  • Rouzbeh Amini

  • Bindi Brook

  • Markus Buehler

  • Zohara Cohen

  • Daniel Einstein

  • Ben Ellis

  • Ahmet Erdemir (co-lead)

  • Trent Guess

  • Jason Halloran

  • Jeffrey Holmes

  • Jay Humphrey (co-lead)

  • Iwona Jasiuk

  • Peter Laz

  • Jia Lu

  • Alison Marsden

  • Jill McNitt-Gray

  • Hongyu Miao

  • Michael Miga

  • James Moore

  • Tina Morrison

  • Madhavan L. Raghavan

  • Vijayaraghavan Rajagopal

  • Ed Sander

  • Grant Schaffner

  • Kevin Shelburne

  • Abbas Shirinifard

  • Jess Snedeker

  • Dalin Tang

  • Darryl Thelen

  • Jeff Weiss

  • Muhammad Zaman (co-lead)

  • Katherine Yanhang Zhang

  • Ahmad Raeisi Najafi

 

MSM Meetings

MSM 2017 (10th Anniversary) meeting Discussion Items

Previous activities (Recap from last year) 

o  Review article on MSM in ASME JBE.

o  WCB 2014 Boston – symposium focusing on women health issues.

o  Difficulty in getting enthusiasm – wide spectrum of perspective in biomechanics, each one has their own set of multiscale models.

 

Suggested Activities

More engagement in education side:

o  T32 grant on MSM with training across in different universities with different emphasis – promote collaboration across universities.

o  T32 – 5 trainees/year across universities in the Midwest focusing on biomechanics at different scales.

·      Put together a curriculum for multiscale biomechanics in the Wiki webpage to attract and educate students:

o  NIBIB funding for the Wiki curriculum

o  Make site more valuable and visible – blog, site

o  Develop and improve on the mission statement for the WG

o  One possible issue: significant overlap with the multiscale modeling WG.

o  One-year physiology class for multiscale biomechanics students.

o  Multiscale modules + lab exercises sharing through the Wiki webpage that fit into various departments such as ME, BME etc. (Will Richardson volunteered to lead)

o  Utilizing MOCC courses in the Wiki site

o  Medical imaging class covering various scales.

o  Professional MS class covering MS modeling.

o  Defining, connecting and simplifying various concepts of multiscale biomechanics to students, including medical students.

·      2 white papers proposed by the steering committee that are geared towards clinician and modelers

o  Provide some translational example from biomechanics WG

o  Post some success stories from the WG on MSM

o  Restructuring the WGs by making the translational WG as a hub of all WGs and have each WG nominating a “translator”.

o  Mechanobiology and signaling as a common theme for bridging clinicians and MSM modelers from various WGs

·      Reach out and make the IMAG more public – not restricted to awardees?

o  Connecting with other professional societies e.g., AHA, ASB, ISB, SB3C.

o  Reach out to the medical domain by involving medical societies (Marvin Slepian to lead)

o  Symposium on MSM in conference organized by other societies, e.g., ORS.

2014 Meeting

Highlights from Breakout Session

Attendees (14 total, 6 current BWG members):

  • Victor Barocas, University of Minnesota
  • Silvia Blemker, University of Virginia
  • Yasin Dhaher, Northwestern University
  • Scott Diamond, University of Pennsylvania
  • Ahmet Erdemir, Cleveland Clinic
  • Jay Humphrey, Yale University
  • Peter Laz, University of Denver
  • Yaling Liu, Lehigh University
  • Michael Mak, Boston University
  • Mohammad Mofrad, UC Berkeley
  • Jimmy Moore, Imperial College
  • Kevin Shelburne, University of Denver
  • Darryl Thelen, University of Wisconsin-Madison
  • Beth Winkelstein, University of Pennsylvania

2013-2014 Activity Summary

  • 3 new members
  • 4 relevant webinars by new grantees
  • 1 discussion session (in lieu of 2013 MSM Consortium Meeting)
  • High visibility on World Congress of Biomechanics 2014
    • 13 MSM sessions; > 60 podium presentations
    • BWG initiated mini-symposium
    • Upcoming special issue in Journal of the Royal Society Interface
  • Upcoming contributions to Computer Methods in Biomechanics and Biomedical Engineering 2014

Ideas for 2015

From 2013 discussion:

  • Theme based multiple speaker webinars
  • Satellite meetings and sessions in conferences of allied fields (clinical or research)
  • Multi-viewpoint perspective articles on multiscale in silico biomechanics
  • Exploration of model sharing venues within and outside IMAG/MSM
  • Proactive submission and review of computational biomechanics proposals in cross-disciplinary review panels
  • Promotion of BWG as a resource for others to nucleate collaborations

From 2014 breakout session:

  • Session organization in in Summer Biomechanics, Bioengineering & Biotransport Conference 2015
  • Contributions to 2015 Biomedical Engineering Society meeting
  • Prioritized new directions (3 among 8)
    • Identification and delivery of success stories
    • Development of a modeling challenge for community to compete
    • Virtual training opportunities

Transfer of Leadership

  • Muhammad Zaman (co-leading since early 2014)
  • New co-lead (soon to be announced)

Attachments

For an update of past activities and ideas for upcoming year, please refer to

bwg_msm2014.ppt83.5 KB

 

For a summary of World Congres of Biomechanics 2014 activities, please refer to

biomechanics_working_group_report.pdf36.24 KB

 

For a summary of breakout session, please refer to

bwg-discussion-2014.pdf70.13 KB

 

Please provide comments for the Biomechanics Working Group breakout session at the bottom of this page.

2013 Meeting

Breakout Discussion Topics

Please provide your feedback to any of the listed topics. If you like, add topics for group discussion.

Summary of 2013 Activities

  • Thematic webinar on April 17, 2013 entitled Bridging biological scales by linking agent-based models to intracellular and continuum biomechanics models by Shayn Peirce-Cottler, University of Virginia

  • A multiscale modeling and simulation session during the conference entitled Computer Methods in Biomechanics and Biomedical Engineering, April 3-6, 2013

Upcoming Initiatives

  • Mini symposia on multiscale modeling and simulation during World Congress of Biomechanics, July 6-11, 2014

Transfer of Leadership

  • Co-leaders are reaching out to relevant U01 grantees to turnover leadership

Potential Collaboration Opportunities

For an update of past and planned activities, please refer to

bwg_msm2013.ppt80.5 KB

 

For a summary of online breakout discussion, please refer to

bwg-discussion-2013.pdf81.76 KB

 

Journal Articles

White papers from the working group (including Working Group 6)

  • Tawhai M, Bischoff J, Einstein D, Erdemir A, Guess T, Reinbolt J. Multiscale modeling in computational biomechanics. IEEE Eng Med Biol Mag. 2009 May-Jun;28(3):41-9. PubMed Central

  • Erdemir A, Guess T, Halloran J, Tadepalli SC, Morrison TM. Considerations for reporting finite element analysis studies in biomechanics. J Biomech. 2012 Feb 23;45(4):625-33. PubMed Central