Conference Reports | Interagency Modeling and Analysis Group

2014

The Value and Impact of Data Sharing and Curation: A synthesis of three recent studies of UK research data centres

Biositemaps Status and Plans

Big Data Government Report:

The First Workshop on Sustainable Software for Science: Practice and Experiences

NCBC Showcase:

Meeting Website

National Academies:

Toward Precision Medicine: Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease, 2011, link
Assessing the Reliability of Complex Models: Mathematical and Statistical Foundations of Verification, Validation, and Uncertainty Quantification, 2012, link

April 2012 ASME Conference Report

Feb 2012 ASME Conference Report

(posted October, 2011) Quantitative and Systems Pharmacology Workshop -- White Paper Report

A white paper is posted, dealing with the interface between systems biology and pharmacology: Quantitative and Systems Pharmacology in the Post-genomic Era: New Approaches to Discovering Drugs and Understanding Therapeutic Mechanisms. This paper is the culmination of two sponsored workshops in the Washington DC area, in 2008 and 2010. The white paper makes the case that this post-genomic era is the right time to develop and employ quantitative, systems approaches to understand drug action more predictively, and that the need and excitement for doing so is building. The overall recommendation of the workshop committee is for pharmacology to move beyond characterizing drug/target interactions to a holistic quantitative understanding of drug action across many levels—from drug-receptor interactions to drug response in humans. As stated in the paper, this will require the participation of scientists from academia and industry who work in diverse areas, including traditional pharmacology, clinical pharmacology, pharmacodynamics/pharmacokinetic modeling, systems biology, chemistry, bioinformatics, multiscale modeling and computer science. Training new and established investigators also will be a critical element.

NIGMS Feedback Loop (posted Monday, Oct 24, 2011), https://loop.nigms.nih.gov/index.php/2011/10/24/emergence-of-quantitative-and-systems-pharmacology-a-white-paper/

June, 2010 NHLBI Working Group Model-Guided Design and Analysis of Genetic and Pharmacogenetic Clinical Trials to Foster Translational Research

The Division of Cardiovascular Sciences of the National Heart, Lung, and Blood Institute (NHLBI) convened a Working Group of multi-disciplinary experts on June 23-24, 2010 in Bethesda, MD to discuss the use of in silico modeling to facilitate translational research. This focus of this Working Group was in alignment with Goals 1, 2, and 3 of the NHLBI Strategic Plan. The purpose of the working group was to discuss the feasibility to perform in silico genetics or pharmacogenetics clinical trials, as well as discuss the best approaches to using these methods to inform the design and conduct of such clinical trials. Meeting participants provided NHLBI with research priorities and recommendations for this field of science.
http://www.nhlbi.nih.gov/meetings/workshops/trans-research.htm

December, 2009 IMAG Futures Meeting -- The Impact of Modeling on Biomedical Research

The Interagency Modeling and Analysis Group (IMAG) held an IMAG Futures Meeting on December 15-16, 2009. This meeting was open to the public to share the discussion of a working group who deliberated on the impact of biomedical, biological and behavioral modeling. This meeting was an opportunity for IMAG to assess to what extent computational modeling has succeeded or failed to make a difference in the broader research endeavor, and to discuss these issues in the context of current challenges and opportunities for biomedical, biological and behavioral modeling, see meeting Charge. Meeting discussions were grouped by five biological scales: 1) Population; 2) Whole-Body; 3) Cell-Tissue-Organ; 4) Pathways and Networks; and 5) Atomic and Molecular.
IFM Announcement
Media:IMAG_Futures_Report.pdf‎

April, 2009 Virtual Tissues 2009 position paper

In 2009 the US Environmental Protection Agency and the European Commission jointly organised an event on the role of tissue modelling in biomedical and environmental research and practice. The event, called Virtual Tissues 2009, included a consensus panel where a group of world-recognised experts from the United States and from Europe discussed the role, the opportunities and the challenges associated with tissues modelling. Now the position paper that summarizes some of the main conclusions is public.