Impact of Genomic Variation on Function (IGVF) Consortium

Seeking Investigators to Join the Impact of Genomic Variation on Function (IGVF) Consortium, Applications Due November 4th

NHGRI encourages applicants for a new program—the Impact of Genomic Variation on Function (IGVF) Consortium—to develop a framework for systematically understanding the effects of genomic variation on genome function and how these effects shape phenotypes.

Investigators with diverse expertise in genetics, genomics, and data science are needed and will be supported through five Funding Opportunity Announcements with applications due on November 4, 2020. 

 

IGVF will be organized as a research consortium that brings investigators together in a highly collaborative effort to examine how genomes function, how genome function shapes phenotypes, and how these processes are influenced by genomic variation. The program will utilize emerging experimental and computational genomic approaches to build a catalog of the impact of genomic variants on genome function and phenotypes.  

 

NHGRI strongly encourages all investigators with innovative ideas aligned with IGVF goals to submit applications, especially investigators from demographic groups or institutions generally underrepresented in genomic science, new investigators, experienced investigators who are new to genomic science, and investigators who have not previously participated in a NHGRI-consortium or program.

 

Informational webinars will be presented September 3, 2020 and September 9, 2020. Please see NOT-HG-20-055 for details.

 

For more information, please review the IGVF Funding Opportunity Announcements (FOAs) below, visit the IGVF website, and reach out to the Scientific Contacts with any questions: 

 

  • RFA-HG-20-043; Systematic Characterization of Genomic Variation on Genome Function and Phenotype (UM1 Clinical Trial Not Allowed). Scientific Contact: Mike Pazin, Ph.D., michael.pazin@nih.gov
  • RFA-HG-20-044; Defining Genomic Influence on Gene Network Regulation (U01 Clinical Trial Not Allowed). Scientific Contact: Daniel Gilchrist, Ph.D., daniel.gilchrist@nih.gov
  • RFA-HG-20-045; Single-cell Profiling of Regulatory Element and Gene Activity in Relationship to Genome Function (UM1 Clinical Trial Not Allowed). Scientific Contact: Stephanie A. Morris, Ph.D., morriss2@mail.nih.gov
  • RFA-HG-20-046; Genomic Variation and Function Data and Administrative Coordinating Center (U24 Clinical Trial Not Allowed). Scientific Contact: Stephanie A. Morris, Ph.D., morriss2@mail.nih.gov
  • RFA-HG-20-047; Developing Predictive Models of the Impact of Genomic Variation on Function (U01 Clinical Trial Not Allowed). Scientific Contact: Daniel Gilchrist, Ph.D., daniel.gilchrist@nih.gov.

 

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