The Pre-Meeting exercises below are provided for all attendees in addition to the speakers of the 2024 IMAG/MSM: Teaming for Biomedical Digital Twin Meeting.

Read About the 2024 Meeting

Exercise #1:  Map your own project to this diagram below.  Consider how your project ideas can be broken up to systems of systems for biomedical digital twins. Take specific note of the following characteristics of digital twins, based on the NASEM Report definition of a digital twin, that go beyond having a virtual/digital representation of a class of objects:

1. Digital Twins are "fit for purpose"; this will affect the level of resolution of a digital twin's computational specification model.

2. There is an ongoing, bidirectional data connection between the virtual and real-world twin.

3. Biomedical digital twins are inherently translational, and the information obtained from the digital twin should affect some decision-making process in the real-world. This means there will be some human interaction (at least initially) in how this process is specified.

4. There are numerous factors to "wrap" the entire project; the one's listed below are a non-exclusive list of major ones identified in the NASEM Report: Verification, Validation and Uncertainty Quantification (VVUQ), Security of the system and Ethical Concerns. These will be dealt with in more detail in the activities on Exercise 2, but Exercise 1 involves the initial identification of requirements in each of these areas.

From the NASEM Foundations for Digital Twins Consensus Study.  Click here for the NASEM website.

Exercise #2: Consider the digital twin challenges below. 

1. Think about these challenges with respect to your own biomedical digital twin project(s).

2. Determine what resources you can provide to address these challenges as it pertains to unique factors in the biomedical domain area, and what additional expertise or capabilities you would require to address challenges in your own project.