A FORTRAN based model for triple-labeled indicator dilution experiments in a four region tissue exchange model with 20 flow paths. WILL NOT RUN ON PC (MS Windows) COMPUTERS IF DOWNLOADED, BUT CAN BE RUN OVER THE WEB AS AN APPLET.
Further reading: Distributed Blood Tissue Exchange Models Explained
Further reading: MMID4 manual (XSIM version)
Description
A FORTRAN based model for triple-labeled indicator dilution experiments in a four region tissue exchange model with 20 flow paths. WILL NOT RUN ON PC COMPUTERS IF DOWNLOADED, BUT CAN BE RUN OVER THE WEB AS AN APPLET.
The manual for the XSIM version is useful in explaining the model. The manual has not been revised for the JSim implementation. Contact garyr at uw dot edu if you need further assistance.
Equations
Vascular Equations
Differential Equation
Left Boundary Condition
Right Boundary Conditions
, 
Initial Conditions
or 
Extracellular Equations
Differential Equations
Left Boundary Conditions
, 
Right Boundary Conditions
, 
, 
Initial Conditions
, 
or 
Permeant Equations
Differential Equations
Left Boundary Conditions
, 
, 
, 
Right Boundary Conditions
, 
, 
, 
, 
Initial Conditions
, 
, 
, 
or 
, , , .
The equations for this model may be viewed by running the JSim model applet and clicking on the Source tab at the bottom left of JSim's Run Time graphical user interface. The equations are written in JSim's Mathematical Modeling Language (MML). See the Introduction to MML and the MML Reference Manual. Additional documentation for MML can be found by using the search option at the Physiome home page.
- Download JSim model MML code (text):
- Download translated SBML version of model (if available):
- No SBML translation currently available.
- Information on SBML conversion in JSim
We welcome comments and feedback for this model. Please use the button below to send comments:
None.
Please cite https://www.imagwiki.nibib.nih.gov/physiome in any publication for which this software is used and send one reprint to the address given below:
The National Simulation Resource, Director J. B. Bassingthwaighte, Department of Bioengineering, University of Washington, Seattle WA 98195-5061.
Model development and archiving support at https://www.imagwiki.nibib.nih.gov/physiome provided by the following grants: NIH U01HL122199 Analyzing the Cardiac Power Grid, 09/15/2015 - 05/31/2020, NIH/NIBIB BE08407 Software Integration, JSim and SBW 6/1/09-5/31/13; NIH/NHLBI T15 HL88516-01 Modeling for Heart, Lung and Blood: From Cell to Organ, 4/1/07-3/31/11; NSF BES-0506477 Adaptive Multi-Scale Model Simulation, 8/15/05-7/31/08; NIH/NHLBI R01 HL073598 Core 3: 3D Imaging and Computer Modeling of the Respiratory Tract, 9/1/04-8/31/09; as well as prior support from NIH/NCRR P41 RR01243 Simulation Resource in Circulatory Mass Transport and Exchange, 12/1/1980-11/30/01 and NIH/NIBIB R01 EB001973 JSim: A Simulation Analysis Platform, 3/1/02-2/28/07.