1. Resources
  2. Models, Tools & Databases
  3. Whole brain images of a Down syndrome mouse model database

Content posted to this wiki are contributions made by the IMAG research community.
Any questions or concerns should be directed to the individual authors. Full disclaimer statement found here. 

Whole brain images of a Down syndrome mouse model database

Description & purpose of resource

Whole brain images of a Down syndrome (DS) mouse model (Ts65Dn). The Thy1-eYFP-H was crossed with Ts65Dn mouse model for imaging excitatory neurons.The images of DS mice model (TS) and their wild type littermates (WT) were acquired with light sheet fluorescence microscopy (MuVi-SPIM, Luxendo), cleared with CLARITY. The whole brain dataset consist of 13 WT (8 males and 5 females) and 17 TS (11 males and 6 females). Magnification: 15x. Voxel resolution: 0.433um x 0.433um x2.00um.

Whole brain Imaging of DS mouse model

 

Spatial scales
cellular
tissue
organ
This resource is currently
under early-stage development
DOI link to publication describing this resource

pending_to_be_publicly_available_at_BIL_repository

Link to resource
https://www.brainimagelibrary.org/index.html
Keywords
whole brain image, Down syndrome mouse model, Ts65Dn, Thy1-eYFP-H
Table sorting checkbox
Off
Model type
topological
geometrical
Data type
expression
fluorescence
imaging