Virtual Imaging Clinical Trials for Regulatory Evaluation (VICTRE)

What is being modeled?

in silico breast radiographic images

Description & purpose of resource

The Virtual Imaging Clinical Trials for Regulatory Evaluation (VICTRE) computer modeling pipeline is a set of tools that allow for the generation of in silico breast radiographic images for the evaluation of digital mammography (DM) and digital breast tomosynthesis (DBT) devices.

Link: https://www.fda.gov/medical-devices/science-and-research-medical-devices/victre-silico-breast-imaging-pipeline

Spatial scales

organ

Temporal scales

days

This resource is currently

mature and useful in ongoing research

Has this resource been validated?

Yes

How has the resource been validated?

VICTRE in silico imaging trials and imaging system computer simulation tools can in some cases be considered viable sources of evidence for the regulatory evaluation of imaging devices.

Can this resource be associated with other resources? (e.g.: modular models, linked tools and platforms)

No

Key publications (e.g. describing or using resource)

Badano, Aldo, Christian G. Graff, Andreu Badal, Diksha Sharma, Rongping Zeng, Frank W. Samuelson, Stephen J. Glick, and Kyle J. Myers. "Evaluation of digital breast tomosynthesis as replacement of full-field digital mammography using an in silico imaging trial." JAMA network open 1, no. 7 (2018): e185474-e185474.

DOI link to publication describing this resource

Sharma, Diksha, Christian G. Graff, Andreu Badal, Rongping Zeng, Purva Sawant, Aunnasha Sengupta, Eshan Dahal, and Aldo Badano. "In silico imaging tools from the VICTRE clinical trial." Medical physics 46, no. 9 (2019): 3924-3928.

Link to resource

https://github.com/DIDSR/VICTRE_PIPELINE

Keywords

In silico imaging; physics-based simulation; virtual clinical trials

Table sorting checkbox

Off

Model type

statistical

Data type

imaging