Bridging the Gap Between Cancer Mechanism and Population Science (U01)

NCI, NIA

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications for projects that bridge biological mechanism to population level scales. By incorporating insights and data from one end of the cancer research spectrum into the framework of the other, projects should be able to cross-validate data gathered at different scales, and explore links between basic biology, population science, and potential health applications in treatment, prevention, diagnosis, and/or screening. Proposed projects should pose a challenging cancer research question that can be addressed by connecting these two ends of the research spectrum that would be difficult to address or explain through biological or epidemiological investigation alone. Only a single cohesive project integrating aspects from these two areas is allowed in each application.

Application Due Date: March 8, 2013; October 4, 2013; etc. More Information

Mechanisms Underlying the Links between Psychosocial Stress, Aging, the Brain and the Body (R01)

(PA-09-216)

Application Due Date(s): Standard dates apply, please see http://grants1.nih.gov/grants/funding/submissionschedule.htm

-until Sept 2012

http://grants.nih.gov/grants/guide/pa-files/PA-09-216.html

This FOA encourages multidisciplinary and interdisciplinary research to elucidate the mechanistic links between psychosocial stress and health in aging, as well as how the aging process and age-related diseases affect the responses to psychosocial stressors. Generally, research should be focused on (1) aging and how neural mechanisms respond to psychosocial stress and affect other body systems, (2) characterizing the behavioral, psychological and social mechanisms and pathways involved in transducing psychosocial stressors into health outcomes, (3) how stressors modulate physiological process underlying life-span, immune mechanisms, and metabolism, and (4) how psychosocial stress contributes to the development or progression of geriatric syndromes, chronic medical conditions, and disabilities in later life. Research is strongly encouraged that aims to identify appropriate targets for intervention, at any level of analysis, from societal to molecular. Research spanning multiple levels of analysis is particularly encouraged. Research focused on oxidative stress or on environmental or physical stressors of a non-psychosocial nature is not appropriate to this FOA.